[NP-Clinical] now a derm question

[debcfnp at aol.com]

Acyclovir is indicated over the age of two.  Valtrex is a prodrug of acylovir and has a category B for nursing and pregnancy so I am not sure safety would be an issue.  Most newer drugs don't have studies on children to establish safety and efficacy.  What is the weight of the child?  
 
I know as a child I had cold sores all the time.  I would have taken anything to have prevented them!!  
I know now as an adult, if I feel one coming and take a Valtrex, it never even starts so I don't know why the efficacy would be in question either.
 
If you don't feel comfortable with valtrex, why not acyclovir?
 
Just my 2 cents
Deb
 
 
 
 
-----Original Message-----
From: sgwiers at hotmail.com
To: np-clinical at nurse.net
Sent: Fri, 11 May 2007 9:16 AM
Subject: [NP-Clinical] now a derm question


Does anyone have any documented evidence of the safety and efficacy of the use of Valtrex for herpes labialis in 12 year olds? My collaborating doc has a 12-year-old boy who experiences significant herpes labialis almost monthly. According to the PDR, studies have included adolescents 12 years and older, but also indicates that efficacy in pre-pubescent children has not be established. 
 
Sue Wiers FNP 
 
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