[NP-Clinical] now a derm question

Sue Wiers sgwiers at hotmail.com
Fri May 11 07:55:49 PDT 2007


Actually, it is my collaborating doc's patient.  I may be mistaken, but I 
believe that Acyclovir does not have an FDA indication for herpes labialis 
and he likes to stick with FDA indications.  The Valtrex rep was just in and 
is going to provide me with the studies that included children.

Thanks to everyone for your responses.

Sue Wiers FNP

>From: debcfnp at aol.com
>Reply-To: NP Clinical <np-clinical at nurse.net>
>To: np-clinical at nurse.net
>Subject: Re: [NP-Clinical] now a derm question
>Date: Fri, 11 May 2007 10:37:18 -0400
>
>Acyclovir is indicated over the age of two.  Valtrex is a prodrug of 
>acylovir and has a category B for nursing and pregnancy so I am not sure 
>safety would be an issue.  Most newer drugs don't have studies on children 
>to establish safety and efficacy.  What is the weight of the child?
>
>I know as a child I had cold sores all the time.  I would have taken 
>anything to have prevented them!!
>I know now as an adult, if I feel one coming and take a Valtrex, it never 
>even starts so I don't know why the efficacy would be in question either.
>
>If you don't feel comfortable with valtrex, why not acyclovir?
>
>Just my 2 cents
>Deb
>
>
>
>
>-----Original Message-----
>From: sgwiers at hotmail.com
>To: np-clinical at nurse.net
>Sent: Fri, 11 May 2007 9:16 AM
>Subject: [NP-Clinical] now a derm question
>
>
>Does anyone have any documented evidence of the safety and efficacy of the 
>use of Valtrex for herpes labialis in 12 year olds? My collaborating doc 
>has a 12-year-old boy who experiences significant herpes labialis almost 
>monthly. According to the PDR, studies have included adolescents 12 years 
>and older, but also indicates that efficacy in pre-pubescent children has 
>not be established.
>
>Sue Wiers FNP
>
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